产品货号：
Z38983
中文名称：
TIMP4抗体
英文名称：
Anti-TIMP4 Antibody (Clone#9:4-7)
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TIMP4 Antibody (Clone#9:4-7) |
| 指标别名 | Metalloproteinase inhibitor 4;TIMP 4;TIMP4;TIMP-4 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IHC |
| 基因名称 | TIMP4 |
| 克隆号 | 9:4-7 |
| 抗体来源 | Mouse |
| 免疫原 | Anti-TIMP4 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with full length human TIMP4 protein followed by hybridoma development. |
| 计算分子量 | 26kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | Anti-TIMP4 was purified from clarified mouse ascetic fluid by Protein A chromatography followed by extensive dialysis against the buffer stated above.TIMP4 antibody is specific for human TIMP4 protein.This antibody reacts with human TIMP4 in tissue sections of formalin-fixed,paraffin-embedded In ELISAs and Native-PAGE,this antibody does not cross-react with recombinant human TIMP-1,-2 or -3.A BLAST analysis was used to suggest cross-reactivity with TIMP4 from human and mouse sources based on the immunizing sequence.Cross-reactivity with TIMP-4 from other sources has not been determined. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Tissue inhibitor of metalloproteinase-4 (TIMP-4) is member of the TIMP family of inhibitors of matrix metalloproteinase (MMP) activities.In addition,TIMPs have non-MMP associated functions,including roles in growth promotion,apoptosis,and angiogenesis.All four members of the TIMP gene family form a similar secondary structure due to the formation of six highly conserved disulfide bonds.It has been reported that some TIMPs,TIMP4 included,can bind a tetraspanin in the plasma membrane,initiating an intra-cellular signaling cascade.Elevated levels of TIMP4 have been associated with breast cancer progression and heart disease. |
| Uniprot ID | Q99727 |
| 基因名全称 | Metalloproteinase inhibitor 4 |
| 推荐稀释比 | ELISA:1:20,000 - 1:100,000 IHC:5～10μg/mL WB:1:2,000 to 1:10,000 |
相关搜索：TIMP4抗体，TIMP4单抗，Anti-TIMP4 Antibody (Clone#9:4-7)